Iminophosphorane Complexes of Palladium(II)
نویسندگان
چکیده
منابع مشابه
Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets.
New stable cationic organogold(III) complexes containing the "pincer" iminophosphorane ligand (2-C(6)H(4)-PPh(2)=NPh) have been prepared by reaction of the previously described [Au{kappa(2)-C,N-C(6)H(4)(PPh(2)=N(C(6)H(5))-2}Cl(2)] 1 and a combination of sodium or silver salts and appropriate ligands. The presence of the P atom in the PR(3) fragment has been used as a "spectroscopic marker" to s...
متن کاملLuminescent iminophosphorane gold, palladium and platinum complexes as potential anticancer agents.
A series of coordination gold(III), palladium(II), and platinum(II) complexes with a luminescent iminophosphorane ligand derived from 8-aminoquinoline [Ph3P=N-C9H6N] (1), have been synthesized and structurally characterized. The coordination palladium(II) and platinum(II) compounds can evolve further, under appropriate conditions, to give stable cyclometalated endo species [M{κ3-C,N,N-C6H4(PPh2...
متن کاملOrganometallic Palladium Complexes with a Water-Soluble Iminophosphorane Ligand as Potential Anticancer Agents.
The synthesis and characterization of a new water-soluble iminophosphorane ligand TPA=N-C(O)-2BrC(6)H(4) (C,N-IM; TPA = 1,3,5-triaza-7-phosphaadamantane) 1 is reported. Oxidative addition of 1 to Pd(2)(dba)(3) affords the orthopalladated dimer [Pd(μ-Br){C(6)H(4)(C(O)N=TPA-kC,N)-2}](2) (2) as a mixture of cis and trans isomers (1:1 molar ratio) where the iminophosphorane moeity behaves as a C,N-...
متن کاملGold(III) iminophosphorane complexes as catalysts in C–C and C–O bond formations
The reaction of K[AuCl4] with AgClO4 and iminophosphorane ligands (N,N-IM) Ph3P@NR [R = CH2-2NC5H4 (1), C(O)-2-NC5H4 (2)] or Ph2PyP@NR [Py = -2-NC5H4; R = Ph (3), C(O)Ph (4)] (mol ratio 1:2.2:1) in acetonitrile affords complexes [AuCl2(N,N-IM)]ClO4 (5–8). These compounds are airand moisture-stable and they have been evaluated in two types of catalytic processes. They have been found to be effec...
متن کاملIminophosphorane-organogold(III) complexes induce cell death through mitochondrial ROS production.
Gold compounds are being investigated as potential antitumor drugs. Some gold(III) derivatives have been shown to induce cell death in solid tumors but their mechanism of action differs from that of cisplatin, since most of these compounds do not bind to DNA. We have explored cellular events triggered by three different iminophosphorane-organogold(III) compounds in leukemia cells (a neutral com...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1975
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.48.2044